Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178876 | 0.87 | SIRT5 (0.42) | SIRT5PRNPALDH1A1MAPTSMN1; SMN2 | |
| Bromide SCHEMBL23143309 | 0.86 | SIRT5 (0.41) | SIRT5PRNPALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23143324 | 0.81 | CYP1A2 (0.45) | SIRT5ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL23143291 | 0.80 | MEN1 (0.38) | SIRT5PRNPALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23143302 | 0.80 | BCHE (0.50) | ALDH1A1MAPTSMN1; SMN2HPGDALOX15 | |
| SCHEMBL23143332 | 0.73 | PABPC1 (0.32) | ALDH1A1PDPK1MAPTABCG2HPGD | |
| SCHEMBL23143299 | 0.73 | KDM4E (0.41) | PRNPALDH1A1MAPTSMN1; SMN2ABCG2 | |
| Bromide SCHEMBL23143282 | 0.72 | KDM4E (0.40) | PRNPALDH1A1MAPTABCG2HPGD | |
| Trifluoroacetic Acid SCHEMBL23143307 | 0.72 | MAPT (0.33) | SIRT5ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL22335511 | 0.71 | HDAC6 (0.36) | SIRT5PRNPALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058592-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-04-01 | — | — | WO | disclosed |