Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963543 | 0.96 | RECQL (0.63) | RECQLPLA2G1BPLA2G2ASMN1; SMN2NR5A2 | |
| SCHEMBL2145736 | 0.96 | RECQL (0.63) | RECQLPLA2G1BPLA2G2ASMN1; SMN2NR5A2 | |
| SCHEMBL2837952 | 0.92 | RECQL (0.57) | RECQLPLA2G1BPLA2G2APLA2G10SMN1; SMN2 | |
| SCHEMBL1963957 | 0.85 | RECQL (0.52) | RECQLPLA2G1BPLA2G2APLA2G10SMN1; SMN2 | |
| SCHEMBL1962739 | 0.83 | SMN1; SMN2 (0.58) | PLA2G1BPLA2G2ASMN1; SMN2MAPK1LMNA | |
| SCHEMBL3830729 | 0.83 | MEN1 (0.57) | PLA2G1BPLA2G2ASMN1; SMN2MAPK1LMNA | |
| SCHEMBL2232537 | 0.82 | RECQL (0.66) | RECQLSMN1; SMN2NR5A2NR5A1MAPK1 | |
| SCHEMBL2306258 | 0.82 | RECQL (0.48) | RECQLPLA2G1BPLA2G2ASMN1; SMN2NR5A2 | |
| SCHEMBL2234409 | 0.82 | RECQL (0.66) | RECQLSMN1; SMN2NR5A2NR5A1MAPK1 | |
| SCHEMBL2232177 | 0.81 | RECQL (0.62) | RECQLSMN1; SMN2NR5A2NR5A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |