Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | AKT1 | P31749 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKCB | P05771 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962739 | 0.88 | SMN1; SMN2 (0.58) | MEN1KMT2AS1PR1LMNAAKT1 | |
| SCHEMBL2145736 | 0.87 | RECQL (0.63) | MEN1KMT2ALMNAAKT1ESR1 | |
| SCHEMBL1963543 | 0.87 | RECQL (0.63) | MEN1KMT2ALMNAAKT1ESR1 | |
| SCHEMBL1962658 | 0.84 | LMNA (0.51) | MEN1KMT2AS1PR1LMNAAKT1 | |
| SCHEMBL3827928 | 0.84 | LMNA (0.51) | MEN1KMT2AS1PR1LMNAAKT1 | |
| SCHEMBL2314609 | 0.83 | RECQL (0.59) | MEN1KMT2ALMNAAKT1ESR1 | |
| SCHEMBL2837952 | 0.82 | RECQL (0.57) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL94022 | 0.82 | ALDH1A1 (0.73) | MEN1KMT2AS1PR1LMNAAKT1 | |
| SCHEMBL93475 | 0.82 | ALDH1A1 (0.73) | MEN1KMT2AS1PR1LMNAAKT1 | |
| Water SCHEMBL93771 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AS1PR1LMNAAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626728-A4 | OXIDIZED LIPIDS AND USES THEREOF IN THE TREATMENT OF INFLAMMATORY DISEASES AND DISORDERS | VASCULAR BIOGENICS LTD (IL) | 2009-09-02 | — | — | EP | disclosed |
| EP-1626728-A2 | OXIDIZED LIPIDS AND USES THEREOF IN THE TREATMENT OF INFLAMMATORY DISEASES AND DISORDERS | Vascular Biogenics Ltd. (IL) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004106486-A2 | OXIDIZED LIPIDS AND USES THEREOF IN THE TREATMENT OF INFLAMMATORY DISEASES AND DISORDERS | VASCULAR BIOGENICS LTD. (IL) | 2004-12-09 | — | — | WO | disclosed |