Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | AKT1 | P31749 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKCB | P05771 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830729 | 0.88 | MEN1 (0.57) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL2233829 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL2145736 | 0.87 | RECQL (0.63) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL1963543 | 0.87 | RECQL (0.63) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL2313176 | 0.86 | LMNA (0.53) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL2314609 | 0.83 | RECQL (0.59) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL10846398 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL10847336 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL10847452 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL10846278 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAAKT1ESR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |