Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315069 | 1.00 | PIN1 (0.59) | PIN1NR1H4FFAR2KDM4ELMNA | |
| SCHEMBL2314623 | 1.00 | PIN1 (0.59) | PIN1NR1H4FFAR2KDM4ELMNA | |
| SCHEMBL2320209 | 0.92 | PIN1 (0.55) | PIN1NR1H4FFAR2MMECNR2 | |
| SCHEMBL2317481 | 0.92 | PIN1 (0.57) | PIN1NR1H4FFAR2KMT2AMME | |
| SCHEMBL2314452 | 0.92 | PIN1 (0.57) | PIN1NR1H4FFAR2KMT2AMME | |
| SCHEMBL2320218 | 0.92 | PIN1 (0.55) | PIN1NR1H4FFAR2MMECNR2 | |
| SCHEMBL2314462 | 0.92 | PIN1 (0.57) | PIN1NR1H4FFAR2KMT2AMME | |
| SCHEMBL2313120 | 0.91 | PIN1 (0.54) | PIN1NR1H4FFAR2MEN1POLB | |
| SCHEMBL2313112 | 0.91 | PIN1 (0.54) | PIN1NR1H4FFAR2MEN1POLB | |
| SCHEMBL2315766 | 0.89 | MME (0.55) | PIN1NR1H4FFAR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |