Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.57 |
| ▸ | MME | P08473 | 5/20 | 0.56 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314462 | 1.00 | PIN1 (0.57) | PIN1MMEFFAR2PSMB8PSMB5 | |
| SCHEMBL2314452 | 1.00 | PIN1 (0.57) | PIN1MMEFFAR2PSMB8PSMB5 | |
| SCHEMBL2316350 | 0.95 | FFAR2 (0.61) | PIN1MMEFFAR2PSMB8PSMB5 | |
| SCHEMBL2316357 | 0.95 | FFAR2 (0.61) | PIN1MMEFFAR2PSMB8PSMB5 | |
| SCHEMBL2315069 | 0.92 | PIN1 (0.59) | PIN1MMEFFAR2CNR2NR1H4 | |
| SCHEMBL2314616 | 0.92 | PIN1 (0.59) | PIN1MMEFFAR2CNR2NR1H4 | |
| SCHEMBL2314623 | 0.92 | PIN1 (0.59) | PIN1MMEFFAR2CNR2NR1H4 | |
| SCHEMBL2312680 | 0.90 | FFAR2 (0.70) | PIN1MMEFFAR2MMEL1NR1H4 | |
| SCHEMBL2312655 | 0.90 | FFAR2 (0.70) | PIN1MMEFFAR2MMEL1NR1H4 | |
| SCHEMBL2312663 | 0.90 | FFAR2 (0.70) | PIN1MMEFFAR2MMEL1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |