SCHEMBL2314697

SCHEMBL2314697

CN(C)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 3/20 0.44
GAA P10253 3/20 0.44
ALDH1A1 P00352 3/20 0.44
TP53 P04637 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CHEK1 O14757 1/20 0.43
NEK2 P51955 1/20 0.43
LIMK1 P53667 1/20 0.43
DYRK1A Q13627 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
TAAR1 Q96RJ0 1/20 0.41
AOC3 Q16853 2/20 0.39
HTR6 P50406 1/20 0.39
NSD2 O96028 1/20 0.39
EGFR P00533 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2867614 0.97 TSHR (0.45) TSHRLMNAMAPTGAAALDH1A1
Hydrochloric Acid SCHEMBL11458687 0.95 TSHR (0.43) TSHRLMNAMAPTGAAALDH1A1
SCHEMBL11104116 0.93 TSHR (0.41) TSHRLMNAMAPTGAAALDH1A1
SCHEMBL10875540 0.81 TSHR (0.45) TSHRLMNAMAPTGAAALDH1A1
SCHEMBL19786 0.79 MAPT (0.46) TSHRLMNAMAPTGAAALDH1A1
SCHEMBL13268242 0.79 TSHR (0.43) TSHRLMNAALDH1A1TAAR1AOC3
SCHEMBL5822596 0.79 TSHR (0.43) TSHRLMNAMAPTGAAALDH1A1
SCHEMBL28566057 0.79 AOC3 (0.46) TSHRLMNAALDH1A1CHEK1NEK2
SCHEMBL4719470 0.79 CYP2A6 (0.43) TSHRLMNAMAPTGAAALDH1A1
SCHEMBL65263 0.78 MAPT (0.55) TSHRLMNAMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945927-A Synthesis method of N, N-dimethyl o-chloroaniline 江苏康恒化工有限公司 2024-04-30 CN claimed
CN-113264844-B Method for preparing aryl amide compound by catalyzing carbonylation of aryl tertiary amine without metal catalytic system 宿州学院 2023-05-02 CN claimed
CN-106892945-A A kind of N-heterocyclic carbine-palladium complex, its preparation method and application 温州大学 2017-06-27 CN claimed
WO-2006060654-A2 PESTICIDAL COMPOSITIONS AND METHODS DIVERGENCE, INC. (US) 2006-06-08 WO claimed
US-20050203067-A1 Pesticidal compositions and methods DIVERGENCE, INC. 2005-09-15 US claimed
US-4283520-A USING A CYANOACETYL CURING AGENT AND A PHENYLUREA ACCELERATOR CIBA-GEIGY CORPORATION (US) 1981-08-11 US claimed
JP-61213841-A None JP disclosed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
CN-117945927-A Synthesis method of N, N-dimethyl o-chloroaniline 江苏康恒化工有限公司 2024-04-30 CN disclosed
CN-117945927-A Synthesis method of N, N-dimethyl o-chloroaniline 江苏康恒化工有限公司 2024-04-30 CN disclosed
CN-117945927-A Synthesis method of N, N-dimethyl o-chloroaniline 江苏康恒化工有限公司 2024-04-30 CN disclosed
WO-2024075696-A1 IMIDAZOPYRIDINE DERIVATIVES WITH BICYCLIC STRUCTURE 公立大学法人横浜市立大学 2024-04-11 WO disclosed
US-4076756-A Process for the preparation of triarylborane E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-28 US disclosed
US-4046815-A Process for the preparation of triarylborane E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-06 US disclosed
US-4045495-A Process for the preparation of triarylboranes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-08-30 US disclosed
US-4045458-A FRIEDEL-CRAFTS CATALYSTS KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1977-08-30 US disclosed
US-4020068-A Chromogenic furoquinoxalines NCR CORPORATION (US) 1977-04-26 US disclosed
US-4003898-A Process for the manufacture of cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-01-18 US disclosed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203067-A1 Pesticidal compositions and methods ACHE, DDT, PTMS TSHR 2997/4885LMNA 1278/4885MAPT 3378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.