SCHEMBL19786

SCHEMBL19786

CN(C)c1cccc(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
GAA P10253 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 4/20 0.42
P2RX7 Q99572 1/20 0.41
PNMT P11086 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.39
LMNA P02545 4/20 0.39
ALDH1A1 P00352 3/20 0.39
GLA P06280 1/20 0.39
CYP2A6 P11509 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
NSD2 O96028 1/20 0.36
EGFR P00533 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3786708 0.87 GAA (0.52) MAPTGAAKDM4ETSHRP2RX7
SCHEMBL2314697 0.79 TSHR (0.47) MAPTGAAKDM4ETSHRLMNA
SCHEMBL20120182 0.78 ALDH1A1 (0.48) MAPTGAAKDM4ETSHRCYP1A2
SCHEMBL5395552 0.78 MAPT (0.44) MAPTGAAKDM4ETSHRCYP1A2
SCHEMBL3787606 0.78 MAPT (0.44) MAPTGAAKDM4ETSHRCYP1A2
SCHEMBL15014150 0.78 PNMT (0.39) KDM4ETSHRPNMTCYP1A2CYP3A4
SCHEMBL28249545 0.78 TSHR (0.37) MAPTGAAKDM4ETSHRPNMT
SCHEMBL8927868 0.77 CYP3A4 (0.40) MAPTGAAKDM4EP2RX7CYP1A2
SCHEMBL6673503 0.77 TSHR (0.44) TSHRPNMTCYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL2867614 0.77 TSHR (0.45) MAPTGAAKDM4ETSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208815-A1 PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-06-27 US disclosed
CN-117866264-A Polyarylene ion exchange membrane and preparation method thereof 南方科技大学 2024-04-12 CN disclosed
US-11897764-B2 Porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-02-13 US disclosed
CN-115551868-A Macrocyclic compounds and uses thereof 特修斯制药公司 2022-12-30 CN disclosed
US-20220098037-A1 PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2022-03-31 US disclosed
US-11242248-B2 Iron porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2022-02-08 US disclosed
US-10414651-B2 Iron porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2019-09-17 US disclosed
US-20190256355-A1 IRON PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2019-08-22 US disclosed
US-20170305769-A1 EFFICIENT, MANGANESE CATALYZED PROCESS TO DECOMPOSE CYANIDE IONS AND HYDROGEN CYANIDE FOR WATER DECONTAMINATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2017-10-26 US disclosed
US-9701557-B2 Efficient, manganese catalyzed process to decompose cyanide ions and hydrogen cyanide for water decontamination THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2017-07-11 US disclosed
US-9527734-B2 Efficient, catalytic and scalable method to produce chlorine dioxide THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2016-12-27 US disclosed
US-20160340189-A1 IRON PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2016-11-24 US disclosed
US-20150090672-A1 EFFICIENT, MANGANESE CATALYZED PROCESS TO DECOMPOSE CYANIDE IONS AND HYDROGEN CYANIDE FOR WATER DECONTAMINATION THE TRUSTEES OF PRINCETON UNIVERSITY 2015-04-02 US disclosed
US-20130209573-A1 EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2013-08-15 US disclosed
WO-2012027216-A1 AN EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11242248-B2 Iron porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide PPOX, FECH, FTH1 MAPT 4324/4885GAA 1180/4885KDM4E 2406/4885
US-20190256355-A1 IRON PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE PPOX, FECH, FTH1 MAPT 4324/4885GAA 1180/4885KDM4E 2406/4885
US-11897764-B2 Porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide PPOX, FECH, CAT MAPT 4258/4885GAA 1035/4885KDM4E 2585/4885
US-10414651-B2 Iron porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide PPOX, FECH, FTH1 MAPT 4324/4885GAA 1180/4885KDM4E 2406/4885
US-20220098037-A1 PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE PPOX, FECH, CAT MAPT 4258/4885GAA 1035/4885KDM4E 2585/4885
US-20240208815-A1 PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE PPOX, FECH, CAT MAPT 4258/4885GAA 1035/4885KDM4E 2585/4885
US-20160340189-A1 IRON PORPHYRAZINES AS EFFICIENT, CATALYTIC AND SCALABLE METHOD TO PRODUCE CHLORINE DIOXIDE PPOX, FECH, FTH1 MAPT 4324/4885GAA 1180/4885KDM4E 2406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.