Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313795 | 1.00 | MME (0.47) | MMEPSMB5PSMB8FFAR2CNR2 | |
| SCHEMBL2314822 | 0.83 | MME (0.49) | MMEPSMB5PSMB8PIN1 | |
| SCHEMBL2314826 | 0.83 | MME (0.49) | MMEPSMB5PSMB8PIN1 | |
| SCHEMBL2312167 | 0.80 | FFAR2 (0.64) | MMEPSMB5FFAR2CNR2PPARG | |
| SCHEMBL2312174 | 0.80 | FFAR2 (0.64) | MMEPSMB5FFAR2CNR2PPARG | |
| SCHEMBL2316497 | 0.79 | FFAR2 (0.60) | MMEPSMB5PSMB8FFAR2CNR2 | |
| SCHEMBL2316507 | 0.79 | FFAR2 (0.60) | MMEPSMB5PSMB8FFAR2CNR2 | |
| SCHEMBL2318821 | 0.77 | MME (0.44) | MMEPSMB5PSMB8ALDH1A1HTT | |
| SCHEMBL2318812 | 0.77 | MME (0.44) | MMEPSMB5PSMB8ALDH1A1HTT | |
| SCHEMBL2317677 | 0.77 | MME (0.50) | MMEPSMB5PSMB8FFAR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |