SCHEMBL2315245

SCHEMBL2315245

O=C(O)CC(Cc1ccc(Cl)cc1)NC(=O)Cc1cccc(Cl)c1

nearest known ligand 0.79

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 3/20 0.79
MMEL1 Q495T6 11/20 0.63
MME P08473 7/20 0.63
PSMB8 P28062 1/20 0.52
PSMB5 P28074 1/20 0.52
ACE P12821 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2315341 1.00 FFAR2 (0.79) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2315240 1.00 FFAR2 (0.79) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2313273 0.94 FFAR2 (0.77) FFAR2MMEL1MMEACE
SCHEMBL2313265 0.94 FFAR2 (0.77) FFAR2MMEL1MMEACE
SCHEMBL2315533 0.92 FFAR2 (0.74) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2315526 0.92 FFAR2 (0.74) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2313700 0.90 MME (0.66) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2313693 0.90 MME (0.66) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2314065 0.90 MME (0.66) FFAR2MMEL1MMEPSMB8PSMB5
SCHEMBL2320630 0.89 FFAR2 (0.71) FFAR2MMEL1MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed