Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.71 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.59 |
| ▸ | GHSR | Q92847 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23483109 | 1.00 | MC4R (0.71) | MC4RIL23RGHSR | |
| SCHEMBL28940915 | 1.00 | MC4R (0.71) | MC4RIL23RGHSR | |
| SCHEMBL23484389 | 0.99 | MC4R (0.69) | MC4RIL23RGHSR | |
| SCHEMBL14511692 | 0.94 | MC4R (0.71) | MC4RIL23RGHSR | |
| SCHEMBL14511696 | 0.91 | MC4R (0.67) | MC4RIL23RGHSR | |
| SCHEMBL20108277 | 0.89 | MC4R (0.61) | MC4RIL23RGHSR | |
| SCHEMBL23430098 | 0.89 | MC4R (0.59) | MC4RGHSR | |
| SCHEMBL30924749 | 0.89 | KISS1R (0.62) | MC4RIL23R | |
| SCHEMBL30014698 | 0.89 | MC4R (0.56) | MC4RIL23R | |
| SCHEMBL28940921 | 0.89 | MC4R (0.56) | MC4RIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10960046-B2 | Method of treating melanocortin-4 receptor pathway-associated disorders | RHYTHM PHARMACEUTICALS, INC. (US) | 2021-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10960046-B2 | Method of treating melanocortin-4 receptor pathway-associated disorders | MC4R, MC5R, MC3R | MC4R 1/4885IL23R 2766/4885GHSR 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.