SCHEMBL231547

SCHEMBL231547

[SiH3]C(CNC1CCCC1)(NC1CCCC1)NC1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
DPP7 Q9UHL4 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PABPC1 P11940 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236235 0.98 KDM4E (0.39) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL233394 0.72 KDM4E (0.36) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL29001161 0.71 KDM4E (0.39) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL9285591 0.69 KDM4E (0.39) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL19020836 0.69 KDM4E (0.39) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL56306 0.68 KDM4E (0.38) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL1222189 0.67 ALDH1A1 (0.45) KDM4EALDH1A1HSD17B10
SCHEMBL18177820 0.67 KDM4E (0.43) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL28235072 0.67 KDM4E (0.43) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL11053891 0.67 KDM4E (0.43) KDM4EDPP7HRH3ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed
US-20100190942-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME TOHO CATALYST CO., LTD. (JP) 2010-07-29 US disclosed
EP-1908767-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME Toho Catalyst Co., Ltd. (JP) 2008-04-09 EP disclosed