SCHEMBL233394

SCHEMBL233394

[SiH3]NC(CNC1CCCCC1)(NC1CCCCC1)NC1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
DPP7 Q9UHL4 2/20 0.32
HRH3 Q9Y5N1 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PABPC1 P11940 1/20 0.32
ANPEP P15144 2/20 0.30
ERAP2 Q6P179 2/20 0.30
RAD52 P43351 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234534 0.98 KDM4E (0.33) KDM4E
SCHEMBL233395 0.77 ALDH1A1 (0.36) KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL236235 0.75 KDM4E (0.39) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL234535 0.74 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL231547 0.72 KDM4E (0.35) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL236234 0.72 ALDH1A1 (0.39) KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL29001161 0.71 KDM4E (0.39) KDM4EDPP7HRH3ALDH1A1HSD17B10
SCHEMBL236315 0.69 ALDH1A1 (0.33) ALDH1A1HSD17B10RAD52
SCHEMBL234648 0.69 ALDH1A1 (0.41) KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL231546 0.69 ALDH1A1 (0.35) KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed