Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLR1A | O95602 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364216 | 0.88 | KDM4E (0.46) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315704 | 0.81 | KDM4E (0.49) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315259 | 0.77 | KDM4E (0.46) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315710 | 0.77 | KDM4E (0.49) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2320290 | 0.76 | KDM4E (0.45) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL9893228 | 0.74 | USP7 (0.41) | CYP1A2 | |
| SCHEMBL2317968 | 0.73 | KDM4E (0.42) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315120 | 0.69 | LMNA (0.48) | KDM4EHSD17B10HPGDALDH1A1DHODH | |
| SCHEMBL9086378 | 0.69 | KDM4E (0.46) | KDM4ECASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL9893189 | 0.69 | TP53 (0.42) | ALDH1A1CYP1A2POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125807-B1 | IMIDAZO[1,2-A]PYRROLO[3,2-C]PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIV LEUVEN KATH (BE) | 2011-08-03 | — | — | EP | disclosed |