Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | POLR1A | O95602 | 2/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315735 | 0.88 | KDM4E (0.45) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315704 | 0.82 | KDM4E (0.49) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315259 | 0.78 | KDM4E (0.46) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315710 | 0.78 | KDM4E (0.49) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2320290 | 0.77 | KDM4E (0.45) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2317968 | 0.74 | KDM4E (0.42) | KDM4ECASP1CASP7HSD17B10NR4A3 | |
| SCHEMBL2315120 | 0.70 | LMNA (0.48) | KDM4EHSD17B10DHODHKMT2ANPC1 | |
| SCHEMBL9086378 | 0.70 | KDM4E (0.46) | KDM4ECASP1CASP7HSD17B10DHODH | |
| SCHEMBL10030820 | 0.70 | CYP1A2 (0.47) | KDM4ECASP1CASP7HSD17B10DHODH | |
| SCHEMBL10030817 | 0.70 | KDM4E (0.44) | KDM4ECASP1CASP7HSD17B10NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125807-B1 | IMIDAZO[1,2-A]PYRROLO[3,2-C]PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIV LEUVEN KATH (BE) | 2011-08-03 | — | — | EP | disclosed |