SCHEMBL2315802

SCHEMBL2315802

O=C(O)C[C@@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)Cc1ccsc1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 11/20 0.64
MME P08473 5/20 0.50
CNR2 P34972 2/20 0.44
PIN1 Q13526 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2315810 1.00 FFAR2 (0.64) FFAR2MMECNR2PIN1
SCHEMBL2312665 0.88 FFAR2 (0.74) FFAR2MMECNR2PIN1
SCHEMBL2312671 0.88 FFAR2 (0.74) FFAR2MMECNR2PIN1
SCHEMBL2316365 0.88 FFAR2 (0.74) FFAR2MMECNR2PIN1
SCHEMBL2314316 0.87 FFAR2 (0.59) FFAR2MMECNR2PIN1
SCHEMBL2314323 0.87 FFAR2 (0.59) FFAR2MMECNR2PIN1
SCHEMBL2317640 0.85 MME (0.59) FFAR2MMECNR2
SCHEMBL2317792 0.85 MME (0.47) FFAR2MMECNR2
SCHEMBL2317645 0.85 MME (0.59) FFAR2MMECNR2
SCHEMBL2317781 0.85 MME (0.47) FFAR2MMECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed