Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 5/20 | 0.58 |
| ▸ | MET | P08581 | 3/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | MERTK | Q12866 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26254967 | 0.86 | MET (0.56) | FGFR2METPDGFRAPDGFRBKDR | |
| SCHEMBL21769162 | 0.86 | MET (0.56) | FGFR2METPDGFRAPDGFRBKDR | |
| SCHEMBL21769423 | 0.84 | FGFR2 (0.57) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL21185496 | 0.83 | PDGFRA (0.58) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL26254832 | 0.83 | FGFR2 (0.62) | FGFR2PDGFRAPDGFRBKDRAXL | |
| SCHEMBL7480761 | 0.83 | FGFR2 (0.78) | FGFR2PDGFRAPDGFRBKDRAXL | |
| SCHEMBL30106509 | 0.82 | MET (0.58) | FGFR2METPDGFRAPDGFRBKDR | |
| SCHEMBL371742 | 0.82 | MET (0.58) | FGFR2METPDGFRAPDGFRBKDR | |
| SCHEMBL22104462 | 0.81 | PDGFRA (0.54) | FGFR2PDGFRAPDGFRBKDRAXL | |
| SCHEMBL1893668 | 0.81 | PDGFRA (0.77) | METPDGFRAKDRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842425-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| EP-3798218-A1 | FUSED-CYCLIC PYRAZOLONE FORMAMIDE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-03-31 | — | — | EP | disclosed |