Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 3/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24444522 | 0.87 | SRC (0.48) | PDGFRAPDGFRBSRCTGFBR1KDR | |
| SCHEMBL30106509 | 0.85 | MET (0.58) | PDGFRAPDGFRBKDRFGFR2EGFR | |
| SCHEMBL371742 | 0.85 | MET (0.58) | PDGFRAPDGFRBKDRFGFR2EGFR | |
| SCHEMBL23158610 | 0.83 | FGFR2 (0.58) | PDGFRAPDGFRBKDRFGFR2 | |
| SCHEMBL12829632 | 0.82 | PDGFRB (0.53) | PDGFRAPDGFRBSRCTGFBR1FGFR2 | |
| SCHEMBL12444104 | 0.81 | PDGFRA (0.76) | PDGFRAPDGFRBKDRFGFR2EGFR | |
| SCHEMBL24292886 | 0.81 | PDGFRB (0.58) | PDGFRAPDGFRBKDRFGFR2EGFR | |
| SCHEMBL3895466 | 0.81 | PDGFRB (0.70) | PDGFRAPDGFRBFGFR2EGFR | |
| SCHEMBL15338425 | 0.80 | PDGFRB (0.61) | PDGFRAPDGFRBSRCTGFBR1FGFR2 | |
| SCHEMBL4400367 | 0.80 | PDGFRB (0.72) | PDGFRAPDGFRBSRCTGFBR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141202-A9 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-08-29 | — | — | WO | disclosed |
| WO-2019141202-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-07-25 | — | — | WO | disclosed |