Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 7/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.61 |
| ▸ | FYN | P06241 | 12/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18861126 | 0.90 | CHEK2 (0.52) | CHEK2CHEK1FYNAXLMERTK | |
| SCHEMBL18860414 | 0.89 | CHEK2 (0.66) | CHEK2CHEK1FYNTGFBR1 | |
| SCHEMBL18860959 | 0.84 | CHEK2 (0.52) | CHEK2CHEK1FYNAXLMERTK | |
| SCHEMBL23158768 | 0.81 | CHEK2 (0.55) | CHEK2CHEK1FYNTGFBR1 | |
| SCHEMBL18861081 | 0.81 | CHEK2 (0.55) | CHEK2CHEK1FYNTGFBR1AXL | |
| SCHEMBL18861183 | 0.81 | CHEK1 (0.48) | CHEK2CHEK1FYNAXLMERTK | |
| SCHEMBL18860437 | 0.77 | FYN (0.69) | CHEK2CHEK1FYNTGFBR1 | |
| SCHEMBL23158772 | 0.77 | AXL (0.47) | CHEK2CHEK1FYNAXLMERTK | |
| SCHEMBL19048404 | 0.76 | CHEK2 (0.65) | CHEK2CHEK1FYNTGFBR1 | |
| SCHEMBL30521707 | 0.75 | FYN (1.00) | CHEK2CHEK1FYNTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |