Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA4 | P22748 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859887 | 0.95 | TTR (0.54) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13299159 | 0.94 | TTR (0.55) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL22859850 | 0.91 | CA12 (0.53) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL22859745 | 0.90 | CA12 (0.53) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL17001513 | 0.88 | TTR (0.59) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL21400978 | 0.83 | TTR (0.62) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL23177655 | 0.83 | PTGS2 (0.47) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL22859848 | 0.82 | TTR (0.53) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL23158572 | 0.81 | TTR (0.52) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL25720672 | 0.81 | TTR (0.60) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021060351-A1 | NSAID-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |
| WO-2021060395-A1 | SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |