SCHEMBL13299159

SCHEMBL13299159

CC(C)(C)OC(=O)NCCOCCOC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 3/20 0.55
▸ CYP2C9 P11712 2/20 0.55
▸ USP2 O75604 1/20 0.55
▸ LMNA P02545 1/20 0.55
▸ TBXA2R P21731 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ PTGS2 P35354 4/20 0.48
▸ PTGS1 P23219 2/20 0.48
▸ AKR1B10 O60218 1/20 0.48
▸ UGT1A9 O60656 1/20 0.48
▸ TRPA1 O75762 1/20 0.48
▸ ABCB11 O95342 1/20 0.48
▸ MT-CO2 P00403 1/20 0.48
▸ ALB P02768 1/20 0.48
▸ CXCL8 P10145 1/20 0.48
▸ UGT1A6 P19224 1/20 0.48
▸ UGT1A1 P22309 1/20 0.48
▸ CXCR1 P25024 1/20 0.48
▸ ADRA1A P35348 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17001513 0.94 TTR (0.59) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL23158640 0.94 TTR (0.51) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL23177655 0.89 PTGS2 (0.47) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL22859887 0.88 TTR (0.54) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL21400978 0.85 TTR (0.62) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL22859850 0.84 CA12 (0.53) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL23158592 0.83 TTR (0.54) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL22859898 0.83 TTR (0.63) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL25718999 0.83 TTR (0.63) TTRCYP2C9USP2LMNATBXA2R
SCHEMBL22859745 0.83 CA12 (0.53) TTRCYP2C9USP2LMNATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024038087-A1 METHOD FOR PREPARING STERILE COMPOSITIONS SYNARTRO AB (SE) 2024-02-22 — — WO disclosed
WO-2024038088-A1 LIQUID FORMULATIONS SYNARTRO AB (SE) 2024-02-22 — — WO disclosed
US-20230190943-A1 ALGINIC ACID DERIVATIVE BONDED TO NONSTEROIDAL ANTI-INFLAMMATORY COMPOUND MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2023-06-22 — — US disclosed
US-11642357-B2 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions SYNARTRO AB (SE) 2023-05-09 — — US disclosed
US-20220168320-A1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS SYNARTRO AB (SE) 2022-06-02 — — US disclosed
EP-3988121-A1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS Synartro AB (SE) 2022-04-27 — — EP disclosed
US-11229656-B2 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions SYNARTRO AB (SE) 2022-01-25 — — US disclosed
EP-3226905-B1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS SYNARTRO AB (SE) 2021-12-22 — — EP disclosed
WO-2021060395-A1 SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION 持田製薬株式会社 2021-04-01 — — WO disclosed
EP-3770180-A1 ALGINIC ACID DERIVATIVE BONDED TO NONSTEROIDAL ANTI-INFLAMMATORY COMPOUND Mochida Pharmaceutical Co., Ltd. (JP) 2021-01-27 — — EP disclosed
US-9403756-B2 N-phenyl anthranilic acid derivatives and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-08-02 — — US disclosed
EP-2203411-B1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF UNIV RAMOT (IL) 2016-01-06 — — EP disclosed
WO-2015128787-A1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS PHARMALINK AB (SE) 2015-09-03 — — WO disclosed
US-20140316008-A1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-10-23 — — US disclosed
US-8765815-B2 N-phenyl anthranilic acid derivatives and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-07-01 — — US disclosed
US-8765815-B2 N-phenyl anthranilic acid derivatives and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-07-01 — — US disclosed
US-20100137296-A1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2010-06-03 — — US disclosed
US-20100137296-A1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2010-06-03 — — US disclosed
WO-2009037707-A2 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-03-26 — — WO disclosed
WO-2009037705-A2 ESTERS OF N-PHENYLANTHRANILIC ACID FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATION RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168320-A1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS CD44, PIGS, HPSE TTR 336/4885CYP2C9 393/4885USP2 915/4885
US-20100137296-A1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF TRPV1, TRPA1, TRPV4 TTR 4167/4885CYP2C9 4025/4885USP2 4465/4885
US-20140316008-A1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF TRPV1, TRPA1, TRPV4 TTR 4167/4885CYP2C9 4025/4885USP2 4465/4885
US-11229656-B2 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions CD44, PIGS, HPSE TTR 335/4885CYP2C9 480/4885USP2 1092/4885
US-20230190943-A1 ALGINIC ACID DERIVATIVE BONDED TO NONSTEROIDAL ANTI-INFLAMMATORY COMPOUND ALG1, ALG8, ALG3 TTR 4779/4885CYP2C9 3313/4885USP2 4101/4885
US-11642357-B2 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions CD44, PIGS, HPSE TTR 336/4885CYP2C9 393/4885USP2 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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