Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.59 |
| ▸ | GAK | O14976 | 5/20 | 0.51 |
| ▸ | KIT | P10721 | 4/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.51 |
| ▸ | FYN | P06241 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158701 | 0.83 | FYN (0.60) | PDGFRBPDGFRAGAKKITFYN | |
| SCHEMBL15342384 | 0.79 | PDGFRB (0.57) | PDGFRBPDGFRA | |
| SCHEMBL14438060 | 0.79 | PDGFRB (0.58) | PDGFRBPDGFRAGAKKITDYRK1A | |
| SCHEMBL24171871 | 0.79 | FYN (0.59) | PDGFRBPDGFRAKITDYRK1AFYN | |
| SCHEMBL8840880 | 0.77 | PDE4A (0.67) | PDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL7157212 | 0.76 | CYP2A6 (0.50) | PDGFRBPDGFRAFYN | |
| SCHEMBL6029081 | 0.75 | PDGFRB (0.58) | PDGFRBPDGFRAGAKKITDYRK1A | |
| SCHEMBL3769943 | 0.75 | PDGFRB (0.58) | PDGFRBPDGFRAGAKKITDYRK1A | |
| SCHEMBL14974281 | 0.75 | PDGFRB (0.58) | PDGFRBPDGFRAGAKKITDYRK1A | |
| SCHEMBL8173835 | 0.75 | PDGFRB (0.64) | PDGFRBPDGFRAGAKKITDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |