Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541896 | 0.90 | PDE4A (0.57) | PDE4AALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL18602370 | 0.88 | CA12 (0.67) | PDE4AALDH1A1CYP3A4CA2CA12 | |
| SCHEMBL1047750 | 0.88 | ACHE (0.67) | PDE4AALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL4533772 | 0.88 | L3MBTL1 (0.62) | PDE4AALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL12333997 | 0.88 | ACHE (0.67) | PDE4AALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL15342384 | 0.88 | PDGFRB (0.57) | PDE4AALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL31042563 | 0.88 | ACHE (0.67) | PDE4AALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL29638816 | 0.88 | CA12 (0.67) | PDE4AALDH1A1CYP3A4CA2CA12 | |
| SCHEMBL17239836 | 0.86 | NFE2L2 (0.58) | PDE4AALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL7140279 | 0.86 | ALDH1A1 (0.59) | PDE4AALDH1A1TSHRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016193748-A1 | COMPOSITION | THE UNIVERSITY OF BIRMINGHAM (GB) | 2016-12-08 | — | — | WO | disclosed |
| US-9469621-B2 | Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20150274689-A1 | METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN | UBE CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| WO-2011118845-A1 | POLYESTER RESIN, AND OPTICAL MATERIALS, FILMS AND IMAGE DISPLAY DEVICES USING THE SAME | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | WO | disclosed |
| US-7947406-B2 | Polymer electrolyte, membrane/electrode assembly, and fuel cell | FUJIFILM CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| US-7947406-B2 | Polymer electrolyte, membrane/electrode assembly, and fuel cell | FUJIFILM CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20070231652-A1 | Polymer Electrolyte, Membrane/Electrode Assembly, and Fuel Cell | FUJIFILM CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-20070231652-A1 | Polymer Electrolyte, Membrane/Electrode Assembly, and Fuel Cell | FUJIFILM CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-5637669-A | THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0529439-B1 | Switchable columnar liquid crystalline systems | HOECHST AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| US-5384068-A | Switchable columnar liquid-crystalline systems | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-24 | — | — | US | disclosed |
| EP-0529439-A1 | Switchable columnar liquid crystalline systems | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274689-A1 | METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN | DDT, CYP1A1, CYP1B1 | PDE4A 4609/4885ALDH1A1 97/4885TSHR 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.