Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | PDE2A | O00408 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.41 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.41 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.41 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.41 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.41 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.41 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.41 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17071853 | 1.00 | SLC7A5 (0.49) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL17069279 | 0.81 | PDE2A (0.51) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL17069278 | 0.81 | PDE2A (0.51) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL17071851 | 0.81 | PDE2A (0.51) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL14180926 | 0.81 | SLC7A5 (0.51) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL14180928 | 0.81 | SLC7A5 (0.51) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL20032388 | 0.79 | PDE2A (0.53) | PDE2APOLBALDH1A1TSHR | |
| SCHEMBL23159327 | 0.79 | PDE2A (0.49) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL17069274 | 0.79 | PDE2A (0.49) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 | |
| SCHEMBL23159328 | 0.79 | SLC7A5 (0.46) | SLC7A5PDE2AEPHX1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, RDX, SULT2A1 | SLC7A5 1502/4885PDE2A 573/4885EPHX1 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.