Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316129 | 1.00 | MME (0.53) | MMEFFAR2MMEL1LMNATP53 | |
| SCHEMBL2312748 | 0.92 | FFAR2 (0.51) | MMEFFAR2MMEL1SMN1; SMN2FDFT1 | |
| SCHEMBL2312753 | 0.92 | FFAR2 (0.51) | MMEFFAR2MMEL1SMN1; SMN2FDFT1 | |
| SCHEMBL2319286 | 0.89 | PIN1 (0.53) | MMEFFAR2MMEL1HSD17B2RAB9A | |
| SCHEMBL2319293 | 0.89 | PIN1 (0.53) | MMEFFAR2MMEL1HSD17B2RAB9A | |
| SCHEMBL2317678 | 0.88 | MME (0.60) | MMEFFAR2MMEL1RAB9AGFER | |
| SCHEMBL2317684 | 0.88 | MME (0.60) | MMEFFAR2MMEL1RAB9AGFER | |
| SCHEMBL2320594 | 0.87 | FFAR2 (0.58) | MMEFFAR2MMEL1LMNAFDFT1 | |
| SCHEMBL2320587 | 0.87 | FFAR2 (0.58) | MMEFFAR2MMEL1LMNAFDFT1 | |
| SCHEMBL2316077 | 0.85 | FFAR2 (0.53) | MMEFFAR2MMEL1FDFT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |