Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 17/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161075 | 0.85 | RIPK1 (0.57) | RIPK1ALDH1A1 | |
| SCHEMBL23170688 | 0.84 | RIPK1 (0.51) | RIPK1ALDH1A1GAA | |
| SCHEMBL19505913 | 0.82 | RIPK1 (0.61) | RIPK1ALDH1A1GAA | |
| SCHEMBL24351038 | 0.78 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL9370156 | 0.78 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL9370866 | 0.78 | RIPK1 (0.62) | RIPK1ALDH1A1GAA | |
| SCHEMBL23161321 | 0.78 | RIPK1 (0.62) | RIPK1ALDH1A1 | |
| SCHEMBL23170336 | 0.77 | RIPK1 (0.59) | RIPK1ALDH1A1GAA | |
| SCHEMBL27276665 | 0.76 | RIPK1 (0.71) | RIPK1 | |
| SCHEMBL22037891 | 0.76 | RIPK1 (0.59) | RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021062199-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-01 | — | — | WO | disclosed |