Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 2/20 | 0.69 |
| ▸ | MME | P08473 | 4/20 | 0.57 |
| ▸ | MMEL1 | Q495T6 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317674 | 1.00 | FFAR2 (0.69) | FFAR2MMEMMEL1MEN1KMT2A | |
| SCHEMBL2320196 | 1.00 | FFAR2 (0.69) | FFAR2MMEMMEL1MEN1KMT2A | |
| SCHEMBL2318355 | 0.88 | KMT2A (0.58) | FFAR2MMEMMEL1MEN1KMT2A | |
| SCHEMBL2318361 | 0.88 | KMT2A (0.58) | FFAR2MMEMMEL1MEN1KMT2A | |
| SCHEMBL2315478 | 0.88 | MEN1 (0.70) | FFAR2MMEMEN1KMT2ALMNA | |
| SCHEMBL2315245 | 0.88 | FFAR2 (0.79) | FFAR2MMEMMEL1ACE | |
| SCHEMBL2315472 | 0.88 | MEN1 (0.70) | FFAR2MMEMEN1KMT2ALMNA | |
| SCHEMBL2315240 | 0.88 | FFAR2 (0.79) | FFAR2MMEMMEL1ACE | |
| SCHEMBL2315341 | 0.88 | FFAR2 (0.79) | FFAR2MMEMMEL1ACE | |
| SCHEMBL2312027 | 0.87 | MEN1 (0.57) | FFAR2MMEMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |