Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 4/20 | 0.54 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316457 | 1.00 | LMNA (0.55) | LMNAMAPTPKMGAAMME | |
| SCHEMBL2313433 | 0.91 | MME (0.50) | LMNAMAPTPKMGAAMME | |
| SCHEMBL2313448 | 0.91 | MME (0.50) | LMNAMAPTPKMGAAMME | |
| SCHEMBL2317282 | 0.86 | MEN1 (0.56) | LMNAMAPTMMEMMEL1ALDH1A1 | |
| SCHEMBL2317287 | 0.86 | MEN1 (0.56) | LMNAMAPTMMEMMEL1ALDH1A1 | |
| SCHEMBL2318931 | 0.85 | MME (0.58) | LMNAGAAMMEMMEL1ALDH1A1 | |
| SCHEMBL2318924 | 0.85 | MME (0.58) | LMNAGAAMMEMMEL1ALDH1A1 | |
| SCHEMBL2315692 | 0.84 | KMT2A (0.53) | LMNAMAPTMMEMMEL1MEN1 | |
| SCHEMBL2315703 | 0.84 | KMT2A (0.53) | LMNAMAPTMMEMMEL1MEN1 | |
| SCHEMBL2315478 | 0.84 | MEN1 (0.70) | LMNAMAPTMMEALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |