Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 14/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 14/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 14/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 14/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 14/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 14/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 14/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23167977 | 0.96 | PRKAB2 (0.37) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23167845 | 0.85 | PRKAB2 (0.54) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23168126 | 0.80 | AAK1 (0.36) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22790098 | 0.79 | PRKAB2 (0.51) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17242475 | 0.77 | KDM4E (0.60) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23612262 | 0.75 | F7 (0.49) | F7F3KDM4EALDH1A1HPGD | |
| SCHEMBL23167556 | 0.75 | NR4A2 (0.56) | F7F3MEN1KMT2A | |
| SCHEMBL23612152 | 0.75 | KDM4E (0.54) | F7F3KDM4EALDH1A1HPGD | |
| SCHEMBL23612237 | 0.74 | F7 (0.71) | F7F3 | |
| SCHEMBL24969847 | 0.74 | ALDH1A1 (0.47) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067805-A1 | OXALAMIDE HETEROBYCYCLIC COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-04-08 | — | — | WO | disclosed |