Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MDH1 | P40925 | 1/20 | 0.51 |
| ▸ | MDH2 | P40926 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546576 | 0.93 | L3MBTL1 (0.62) | L3MBTL1MAPTMDH1MDH2SIGMAR1 | |
| SCHEMBL23632422 | 0.88 | MAPT (0.63) | L3MBTL1MAPTMDH1MDH2SIGMAR1 | |
| SCHEMBL18083722 | 0.83 | HIF1A (0.69) | MAPTSIGMAR1FAAHKDM4EALDH1A1 | |
| SCHEMBL1512471 | 0.82 | RORC (0.67) | L3MBTL1MAPTVEGFAEGLN1PLA2G7 | |
| SCHEMBL22800906 | 0.82 | VEGFA (0.54) | L3MBTL1MAPTVEGFAEGLN1PLA2G7 | |
| SCHEMBL27502582 | 0.81 | HRH3 (0.62) | L3MBTL1MAPTGPR119MEN1KMT2A | |
| SCHEMBL23257401 | 0.81 | VEGFA (0.53) | L3MBTL1MAPTALDH1A1PPARDPPARA | |
| SCHEMBL2902092 | 0.80 | KDM1A (0.55) | VEGFAEGLN1 | |
| SCHEMBL12514771 | 0.80 | VEGFA (0.45) | MAPTKDM4EVEGFAEGLN1GPR119 | |
| SCHEMBL23257678 | 0.80 | VEGFA (0.52) | L3MBTL1MAPTVEGFAEGLN1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067805-A1 | OXALAMIDE HETEROBYCYCLIC COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-04-08 | — | — | WO | disclosed |