Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168383 | 0.91 | ALDH1A1 (0.47) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL23168348 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL23168370 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL23168346 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL23168559 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDUSP2AKR1C3SMN1; SMN2 | |
| SCHEMBL23168406 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL23168350 | 0.78 | FPR1 (0.44) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL29277841 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDUSP2GFERAKR1C3 | |
| SCHEMBL22465998 | 0.74 | MAPT (0.50) | ALDH1A1USP2GFERNPC1RAB9A | |
| SCHEMBL609322 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HPGDUSP2AKR1C3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634955-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-31 | — | — | EP | disclosed |