⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601260 | 0.67 | — | — | |
| SCHEMBL1609586 | 0.63 | — | — | |
| SCHEMBL474753 | 0.62 | TSHR (0.31) | — | |
| SCHEMBL17245051 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL2021913 | 0.60 | ALDH1A1 (0.36) | — | |
| SCHEMBL13564242 | 0.60 | — | — | |
| SCHEMBL51455 | 0.58 | — | — | |
| SCHEMBL4155595 | 0.58 | — | — | |
| SCHEMBL6782280 | 0.58 | — | — | |
| SCHEMBL134356 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989030-B2 | Silicone resin and silicone composition | DOW CORNING CORPORATION (US) | 2011-08-02 | — | — | US | disclosed |
| US-20090226609-A1 | Silicone Resin and Silicone Composition | DOW CORNING CORPORATION | 2009-09-10 | — | — | US | disclosed |
| EP-2046893-A2 | SILICONE RESIN AND SILICONE COMPOSITION | Dow Corning Corporation (US) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008018981-A2 | SILICONE RESIN AND SILICONE COMPOSITION | DOW CORNING CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |