Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 7/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22332273 | 0.91 | CYP2D6 (0.41) | CYP2D6KCNH2HRH3UBE2MDCUN1D1 | |
| SCHEMBL23168732 | 0.87 | HRH3 (0.38) | CYP2D6KCNH2HRH3 | |
| SCHEMBL19040733 | 0.84 | UBE2M (0.31) | UBE2MDCUN1D1 | |
| SCHEMBL21776124 | 0.80 | UBE2M (0.34) | UBE2MDCUN1D1OPRM1OPRL1 | |
| SCHEMBL26627398 | 0.80 | MEN1 (0.34) | CYP2D6KCNH2HRH3KMT2A | |
| SCHEMBL21025310 | 0.78 | HRH3 (0.50) | CYP2D6KCNH2HRH3 | |
| SCHEMBL4099236 | 0.78 | HRH3 (0.50) | CYP2D6KCNH2HRH3 | |
| SCHEMBL1104717 | 0.78 | HRH3 (0.50) | CYP2D6KCNH2HRH3 | |
| SCHEMBL26530253 | 0.77 | HRH3 (0.39) | CYP2D6KCNH2HRH3KMT2APAX8 | |
| SCHEMBL24139965 | 0.76 | DRD2 (0.40) | CYP2D6KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057872-A1 | PROTAC SMALL MOLECULE COMPOUND AND APPLICATION THEREOF | 珠海宇繁生物科技有限责任公司 | 2021-04-01 | — | — | WO | disclosed |