Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820993 | 0.87 | MKNK1 (0.42) | MEN1KMT2AMKNK1MKNK2BRD4 | |
| SCHEMBL23168794 | 0.86 | HPGD (0.43) | MEN1KMT2AMKNK1MKNK2BRD4 | |
| SCHEMBL29821674 | 0.84 | MEN1 (0.40) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL23168654 | 0.76 | MAPT (0.51) | MEN1KMT2AALDH1A1ADRA1D | |
| SCHEMBL29821419 | 0.76 | MAPT (0.51) | MEN1KMT2AALDH1A1ADRA1D | |
| SCHEMBL23168928 | 0.75 | THRB (0.38) | MKNK1MKNK2THRATHRB | |
| SCHEMBL23168940 | 0.75 | MAPT (0.40) | KMT2ATHRATHRB | |
| SCHEMBL23168931 | 0.75 | NPBWR1 (0.46) | — | |
| SCHEMBL23168775 | 0.75 | MAPT (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL24819269 | 0.74 | NPBWR1 (0.50) | MKNK1MKNK2THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057791-A1 | CHEMICAL COMPOUND AS THYROID HORMONE BETA RECEPTOR AGONIST AND USE THEREOF | 广东东阳光药业有限公司 | 2021-04-01 | — | — | WO | disclosed |