Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11960695 | 0.77 | MEN1 (0.33) | USP2CASP1CASP7MEN1BRCA1 | |
| SCHEMBL10119694 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL20161610 | 0.66 | MEN1 (0.32) | USP2CASP1CASP7MEN1BRCA1 | |
| SCHEMBL27960232 | 0.64 | PRMT1 (0.33) | ALDH1A1MAPTTDP1 | |
| SCHEMBL22246110 | 0.64 | — | — | |
| SCHEMBL23643488 | 0.61 | NR1H2 (0.38) | USP2MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL30139973 | 0.60 | MEN1 (0.30) | USP2CASP1CASP7MEN1BRCA1 | |
| SCHEMBL18011850 | 0.58 | ALDH1A1 (0.45) | USP2CASP1CASP7MEN1BRCA1 | |
| SCHEMBL18646469 | 0.58 | NR1H2 (0.30) | NR1H2NR1H3 | |
| SCHEMBL6342924 | 0.58 | ALDH1A1 (0.62) | USP2CASP1CASP7MEN1BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390571-B1 | CINNAMIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-03-31 | — | — | EP | disclosed |