Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22631927 | 0.84 | NR1H2 (0.33) | NR1H2NR1H3MEN1USP2KMT2A | |
| SCHEMBL6850987 | 0.71 | GSK3A (0.44) | NR1H2NR1H3MEN1USP2KMT2A | |
| SCHEMBL15196173 | 0.66 | KDM4E (0.34) | NR1H2NR1H3 | |
| SCHEMBL15292003 | 0.64 | NR1H2 (0.32) | NR1H2NR1H3 | |
| SCHEMBL802733 | 0.62 | ALDH1A1 (0.40) | MEN1KMT2ACASP3GSK3AGSK3B | |
| SCHEMBL23169728 | 0.61 | USP2 (0.39) | NR1H2NR1H3MEN1USP2KMT2A | |
| SCHEMBL2378877 | 0.60 | GSK3A (0.35) | CASP3GSK3AGSK3BMGLL | |
| SCHEMBL22342866 | 0.60 | ALDH1A1 (0.35) | MEN1KMT2ACASP3GSK3AGSK3B | |
| SCHEMBL19506224 | 0.60 | GSK3A (0.35) | MEN1KMT2ACASP3GSK3AGSK3B | |
| SCHEMBL7181082 | 0.60 | GSK3A (0.35) | MEN1KMT2ACASP3GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848436-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2021-07-14 | — | — | EP | disclosed |