Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317527 | 0.87 | KDM4E (0.45) | LMNASMN1; SMN2ALDH1A1TDP1NPC1 | |
| SCHEMBL2315823 | 0.87 | KDM4E (0.46) | LMNASMN1; SMN2ALDH1A1TDP1NPC1 | |
| SCHEMBL2317049 | 0.84 | KDM4E (0.42) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL2314524 | 0.81 | MGLL (0.56) | SMN1; SMN2MGLLNPC1RAB9AKDM4E | |
| SCHEMBL2319621 | 0.80 | KDM4E (0.47) | LMNASMN1; SMN2ALDH1A1TDP1KDM4E | |
| SCHEMBL2319328 | 0.79 | KMT2A (0.53) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL7524447 | 0.76 | HTR1B (0.53) | LMNACTSLSMN1; SMN2HTR1BALDH1A1 | |
| SCHEMBL453710 | 0.75 | HTR1B (0.52) | LMNASMN1; SMN2HTR1BALDH1A1TDP1 | |
| SCHEMBL17350670 | 0.74 | MEN1 (0.38) | LMNACTSLSMN1; SMN2ATMALDH1A1 | |
| SCHEMBL2320800 | 0.73 | FABP7 (0.38) | LMNASMN1; SMN2L3MBTL1MGLLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354845-B1 | Photopolymer Composition for the Manufacturing of Holographic Media | COVESTRO DEUTSCHLAND AG (DE) | 2015-12-23 | — | — | EP | claimed |
| EP-2354845-B1 | Photopolymer Composition for the Manufacturing of Holographic Media | COVESTRO DEUTSCHLAND AG (DE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2354845-A1 | (Meth)acrylate writing monomers | Bayer MaterialScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |