SCHEMBL453710

SCHEMBL453710

C=C(CCCOc1ccc(Br)cc1Br)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 1/20 0.52
TDP1 Q9NUW8 2/20 0.46
KDM4E B2RXH2 9/20 0.44
LMNA P02545 4/20 0.44
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 1/20 0.43
USP2 O75604 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524447 0.93 HTR1B (0.53) HTR1BTDP1KDM4ELMNAALDH1A1
SCHEMBL452884 0.82 KDM4E (0.53) KDM4ELMNAALDH1A1SMN1; SMN2KMT2A
SCHEMBL150208 0.81 TDP1 (0.38) TDP1KDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL449703 0.80 THRA (0.44) TDP1KDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL29419306 0.80 HTR1B (0.55) HTR1BTDP1LMNAALDH1A1SMN1; SMN2
SCHEMBL511290 0.80 HTR1B (0.55) HTR1BTDP1LMNAALDH1A1SMN1; SMN2
SCHEMBL28554000 0.79 CYSLTR2 (0.52) HTR1BTDP1KDM4ELMNAALDH1A1
SCHEMBL3187267 0.78 RAB9A (0.49) KDM4EALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL148282 0.78 TDP1 (0.39) TDP1KDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL2317239 0.75 LMNA (0.40) HTR1BTDP1KDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-20210223690-A1 PHOTOCURABLE COMPOSITION FOR IMPRINT, METHOD FOR PRODUCING FILM USING THE SAME, METHOD FOR PRODUCING OPTICAL COMPONENT USING THE SAME, METHOD FOR PRODUCING CIRCUIT BOARD USING THE SAME, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT USING THE SAME CANON KK (JP) 2021-07-22 US disclosed
US-11003073-B2 Photocurable composition for imprint, method for producing film using the same, method for producing optical component using the same, method for producing circuit board using the same, and method for producing electronic component using the same CANON KABUSHIKI KAISHA (JP) 2021-05-11 US disclosed
EP-2841255-B1 RESIN PRODUCTION METHOD AND RESIN PRODUCTION APPARATUS CANON KK (JP) 2020-05-13 EP disclosed
US-10293543-B2 Method of producing a patterned film CANON KABUSHIKI KAISHA (JP) 2019-05-21 US disclosed
EP-2758987-B1 METHOD OF FORMING A FILM CANON KK (JP) 2019-03-20 EP disclosed
US-10208183-B2 Curable composition, film, and method of producing film CANON KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-9982102-B2 Photocurable composition and method of manufacturing film using the composition CANON KABUSHIKI KAISHA (JP) 2018-05-29 US disclosed
US-9885910-B2 Twisted alignment mode liquid crystal display device FUJIFILM CORPORATION (JP) 2018-02-06 US disclosed
EP-2847235-B1 PHOTOCURABLE COMPOSITION AND METHOD OF MANUFACTURING FILM USING THE COMPOSITION CANON KK (JP) 2017-11-22 EP disclosed
US-20090297991-A1 Method for manufacturing lenticular sheet FUJIFILM CORPORATION (JP) 2009-12-03 US disclosed
US-20090233103-A1 RADIOACTIVE RAY-CURABLE RESIN COMPOSITION FOR USE IN OPTICAL MEMBER AND OPTICAL MEMBER JSR CORPORATION (JP) 2009-09-17 US disclosed
US-20090230577-A1 METHOD OF PRODUCING INDENTED SHEET FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
EP-2087271-A1 BACKLIGHT UNIT FUJIFILM Corporation (JP) 2009-08-12 EP disclosed
EP-1998947-A1 METHOD OF PRODUCING INDENTED SHEET FUJIFILM Corporation (JP) 2008-12-10 EP disclosed
WO-2008053790-A1 BACKLIGHT UNIT FUJIFILM CORPORATION (JP) 2008-05-08 WO disclosed
US-20080039546-A1 Photocurable Composition and Optical Part JSR CORPORATION (JP) 2008-02-14 US disclosed
US-20080013341-A1 OPTICAL FUNCTIONAL SHEET, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-01-17 US disclosed
WO-2007111341-A1 METHOD OF PRODUCING INDENTED SHEET FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed
US-20050256219-A1 Photocurable resin composition and optical component JSR CORPORATION (JP) 2005-11-17 US disclosed