Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036708 | 0.84 | ALDH1A1 (0.62) | HSD17B10HPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1663220 | 0.83 | ALDH1A1 (0.53) | HSD17B10HPGDALDH1A1KDM4ECNR2 | |
| SCHEMBL5716237 | 0.82 | DRD2 (0.47) | HSD17B10HPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27921167 | 0.81 | HPGD (0.51) | HSD17B10HPGDALDH1A1KDM4ECNR2 | |
| SCHEMBL21722389 | 0.81 | HPGD (0.59) | HSD17B10HPGDALDH1A1KDM4ECNR2 | |
| SCHEMBL22053016 | 0.81 | ALDH1A1 (0.51) | HSD17B10HPGDALDH1A1KDM4ECNR2 | |
| SCHEMBL21177109 | 0.81 | HPGD (0.59) | HSD17B10HPGDALDH1A1KDM4ECNR2 | |
| SCHEMBL36944169 | 0.81 | ALDH1A1 (0.51) | HSD17B10HPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16943038 | 0.81 | ALDH1A1 (0.51) | HSD17B10HPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9059762 | 0.81 | ALDH1A1 (0.59) | HSD17B10HPGDALDH1A1KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190490-A1 | OXAZOLOPYRIMIDINES AS EDG-1 RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190490-A1 | OXAZOLOPYRIMIDINES AS EDG-1 RECEPTOR AGONISTS | EDNRA, OXGR1, EDF1 | HSD17B10 3628/4885HPGD 588/4885ALDH1A1 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.