SCHEMBL23174646

SCHEMBL23174646

FC(F)(F)c1cc(C(F)(F)F)c([GaH2])c(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.40
TSHR P16473 5/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HIF1A Q16665 1/20 0.35
TXNRD1 Q16881 1/20 0.35
TXNRD3 Q86VQ6 1/20 0.35
TXNRD2 Q9NNW7 1/20 0.35
CACNA1H O95180 5/20 0.35
CACNA1C Q13936 2/20 0.35
CACNA1B Q00975 1/20 0.35
IDO1 P14902 2/20 0.33
CACNA1G O43497 1/20 0.32
MAPK1 P28482 2/20 0.32
AR P10275 1/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11603910 0.77 CES2 (0.43) CES2TSHRALDH1A1CYP3A4TDP1
SCHEMBL6756054 0.74 CES2 (0.41) CES2TSHRALDH1A1CYP3A4TDP1
SCHEMBL15933661 0.74 CES2 (0.41) CES2TSHRALDH1A1CACNA1HCACNA1C
SCHEMBL3194447 0.72 CES2 (0.45) CES2TSHRALDH1A1CYP3A4TDP1
SCHEMBL3174890 0.72 CES2 (0.40) CES2TSHRALDH1A1CYP3A4TDP1
SCHEMBL6537458 0.72 CES2 (0.40) CES2TSHRALDH1A1CACNA1HCACNA1C
SCHEMBL16554203 0.72 CES2 (0.40) CES2TSHRALDH1A1CYP3A4TDP1
SCHEMBL23174658 0.72 CES2 (0.40) CES2TSHRALDH1A1CYP3A4TDP1
SCHEMBL3190814 0.72 CES2 (0.40) CES2CACNA1HCACNA1CCACNA1BIDO1
SCHEMBL1042998 0.72 CES2 (0.40) CES2TSHRALDH1A1CACNA1HCACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703939-A Curable composition, cured product, cured film, display panel, and method for producing cured film 东京应化工业株式会社 2023-02-17 CN disclosed
CN-114675489-A Curable resin composition, cured product thereof, method for producing cured film, and method for producing microlens 东京应化工业株式会社 2022-06-28 CN disclosed
CN-114502613-A Curable composition, cured product, and method for forming cured product 东京应化工业株式会社 2022-05-13 CN disclosed
WO-2021065796-A1 CURABLE COMPOSITION, CURED MATERIAL, AND METHOD FOR FORMING CURED MATERIAL 東京応化工業株式会社 2021-04-08 WO disclosed