Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695382 | 0.85 | CYP1A2 (0.43) | KDM4ECYP1A2CYP3A4CYP2D6FEN1 | |
| SCHEMBL17673814 | 0.81 | PDGFRA (0.36) | SMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL29796752 | 0.77 | ALDH1A1 (0.44) | KDM4ELMNACYP1A2CYP3A4FEN1 | |
| SCHEMBL23174744 | 0.77 | ALDH1A1 (0.44) | KDM4ELMNACYP1A2CYP3A4FEN1 | |
| SCHEMBL7073025 | 0.75 | GPR3 (0.43) | KDM4ELMNACYP1A2CYP2D6FEN1 | |
| SCHEMBL8234895 | 0.75 | ALDH1A1 (0.43) | KDM4ELMNASMN1; SMN2CNR1CNR2 | |
| SCHEMBL15229716 | 0.75 | HDAC6 (0.52) | KDM4ELMNAFEN1ALDH1A1HPGD | |
| SCHEMBL20548896 | 0.73 | KDM4E (0.44) | KDM4ECYP1A2FEN1SMN1; SMN2CCR4 | |
| SCHEMBL1894540 | 0.73 | FEN1 (0.44) | KDM4ECYP1A2CYP3A4FEN1SMN1; SMN2 | |
| SCHEMBL1273316 | 0.73 | CCR4 (0.39) | KDM4EFEN1CCR4CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761082-A | Azepane derivatives | 日本化学药品株式会社 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021065898-A1 | AZEPAN DERIVATIVE | 日本ケミファ株式会社 | 2021-04-08 | — | — | WO | disclosed |