Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 4/20 | 0.65 |
| ▸ | MME | P08473 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317493 | 1.00 | FFAR2 (0.65) | FFAR2MMERAB9ANPC1POLB | |
| SCHEMBL2312665 | 0.86 | FFAR2 (0.74) | FFAR2MMECNR2PIN1 | |
| SCHEMBL2312671 | 0.86 | FFAR2 (0.74) | FFAR2MMECNR2PIN1 | |
| SCHEMBL2316365 | 0.86 | FFAR2 (0.74) | FFAR2MMECNR2PIN1 | |
| SCHEMBL2314791 | 0.86 | HPGD (0.60) | FFAR2MMERAB9ANPC1POLB | |
| SCHEMBL2319212 | 0.86 | MME (0.62) | FFAR2MMERAB9ANPC1POLB | |
| SCHEMBL2314782 | 0.86 | HPGD (0.60) | FFAR2MMERAB9ANPC1POLB | |
| SCHEMBL2319208 | 0.86 | MME (0.62) | FFAR2MMERAB9ANPC1POLB | |
| SCHEMBL2364855 | 0.85 | FFAR2 (0.77) | FFAR2MMECNR2PIN1 | |
| SCHEMBL2364853 | 0.85 | FFAR2 (0.77) | FFAR2MMECNR2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |