Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319208 | 1.00 | MME (0.62) | MMEMEN1KMT2APOLBFFAR2 | |
| SCHEMBL2314782 | 0.88 | HPGD (0.60) | MMEMEN1KMT2APOLBFFAR2 | |
| SCHEMBL2314791 | 0.88 | HPGD (0.60) | MMEMEN1KMT2APOLBFFAR2 | |
| SCHEMBL2317682 | 0.87 | FFAR2 (0.50) | MMEMEN1KMT2APOLBFFAR2 | |
| SCHEMBL2317691 | 0.87 | FFAR2 (0.50) | MMEMEN1KMT2APOLBFFAR2 | |
| SCHEMBL2317493 | 0.86 | FFAR2 (0.65) | MMEPOLBFFAR2MMEL1PKM | |
| SCHEMBL2317495 | 0.86 | FFAR2 (0.65) | MMEPOLBFFAR2MMEL1PKM | |
| SCHEMBL2314965 | 0.84 | MME (0.71) | MMEKMT2AFFAR2MMEL1PSMB8 | |
| SCHEMBL2314959 | 0.84 | MME (0.71) | MMEKMT2AFFAR2MMEL1PSMB8 | |
| SCHEMBL2317467 | 0.84 | MME (0.56) | MMEMEN1KMT2APOLBFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |