Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323313 | 0.76 | GAA (0.60) | PARP1LMNAALOX15 | |
| SCHEMBL29358961 | 0.76 | GAA (0.60) | PARP1LMNAALOX15 | |
| SCHEMBL24699605 | 0.75 | PARP10 (0.46) | CA12CA9CLK4DYRK1BCDK5 | |
| SCHEMBL2171078 | 0.72 | PKM (0.50) | CA12CA9KDM4EPARP1TDP1 | |
| SCHEMBL331587 | 0.72 | PKM (0.50) | CA12CA9KDM4EPARP1TDP1 | |
| Biphenyl SCHEMBL28612860 | 0.70 | GAA (0.53) | KDM4ECLK4DYRK1BLMNAALDH1A1 | |
| SCHEMBL2604370 | 0.69 | MAOB (0.43) | CA12CA9KDM4ETDP1LMNA | |
| SCHEMBL29366641 | 0.69 | MAOB (0.43) | CA12CA9KDM4ETDP1LMNA | |
| SCHEMBL352852 | 0.69 | FABP6 (0.60) | CA12CA9KDM4EPARP1TDP1 | |
| SCHEMBL29463796 | 0.69 | FABP6 (0.60) | CA12CA9KDM4EPARP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066578-A1 | BICYCLIC COMPOUND AND USE THEREOF | 에스케이바이오팜 주식회사 | 2021-04-08 | — | — | WO | disclosed |