SCHEMBL29366641

SCHEMBL29366641

O=C1CC(=O)c2ccccc2O1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.43
ADORA3 P0DMS8 3/20 0.43
KDM4E B2RXH2 3/20 0.43
AR P10275 2/20 0.43
CYP19A1 P11511 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALOX15 P16050 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PKM P14618 1/20 0.42
TSHR P16473 1/20 0.42
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
STK17B O94768 1/20 0.39
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
MAOA P21397 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HSD11B1 P28845 1/20 0.38
AKR1C3 P42330 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604370 1.00 MAOB (0.43) MAOBADORA3KDM4EARCYP19A1
SCHEMBL11455576 0.81 ALOX15 (0.41) MAOBADORA3KDM4EARCYP19A1
SCHEMBL2791149 0.79 PKM (0.39) MAOBKDM4EALOX15TDP1PKM
SCHEMBL4427203 0.79 MAOA (0.61) MAOBADORA3KDM4EARCYP19A1
SCHEMBL8470861 0.79 MAOB (0.41) MAOBADORA3KDM4EARCYP19A1
SCHEMBL29474941 0.79 PKM (0.39) MAOBKDM4EALOX15TDP1PKM
SCHEMBL9642273 0.79 MAPT (0.46) MAOBHSD17B10TDP1CA9ALDH1A1
SCHEMBL15763902 0.79 MAOA (0.46) MAOBKDM4EHSD17B10ALOX15TDP1
SCHEMBL29183932 0.76 MAOB (0.39) MAOBADORA3KDM4EARCYP19A1
SCHEMBL12852223 0.76 HTR2A (0.40) MAOBKDM4EHSD17B10ALOX15MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446731-B Polyurethane foams with low aldehyde emission levels 陶氏环球技术有限责任公司 2022-06-07 CN claimed
US-12503395-B2 Fluidizing compounds for hydraulic compositions CHRYSO (FR) 2025-12-23 US disclosed
US-20250093350-A1 FAB-LINKED GLYCANS AS BIOMARKER FOR THE TRANSITION FROM A PRE DISEASE \"AT-RISK-PHASE\" TO RHEUMATOID ARTHRITIS, AAV OR SJÖGREN SYNDROME ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2025-03-20 US disclosed
US-12158468-B2 Fab-linked glycans as biomarker for the transition from a pre-disease “at-risk-phase” to rheumatoid arthritis; AAV or Sjögren syndrome ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2024-12-03 US disclosed
US-20230095714-A1 FLUIDIZING COMPOUNDS FOR HYDRAULIC COMPOSITIONS STARCIN HOLDING FRANCE (FR) 2023-03-30 US disclosed
EP-4118128-A1 PROCESS FOR REDUCING ALDEHYDE EMISSIONS IN POLYETHER POLYOLS AND POLYURETHANE FOAMS Dow Global Technologies LLC (US) 2023-01-18 EP disclosed
CN-115304614-A Fluorescent probe for detecting aluminum ions and preparation method and application thereof 贵州民族大学 2022-11-08 CN disclosed
CN-115279818-A Fluidizing compound for hydraulic compositions CHRYSO公司 2022-11-01 CN disclosed
CN-216394728-U Electromagnetic heating herbaceous cake 双维科技(珠海)有限公司 2022-04-29 CN disclosed
WO-2022036040-A1 SYNTHESIS OF SMALL MOLECULES INSPIRED BY PHOMOXANTHONE A WORCESTER POLYTECHNIC INSTITUTE (US) 2022-02-17 WO disclosed
US-20220048879-A1 Synthesis of small molecules inspired by Phomoxanthone A WORCESTER POLYTECHNIC INSTITUTE 2022-02-17 US disclosed
CN-110357891-B Chromone-substituted 2-hydroxypyrrole derivative and synthesis method and application thereof 云南大学 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048879-A1 Synthesis of small molecules inspired by Phomoxanthone A ERG28, SQLE, PHKA1 MAOB 674/4885ADORA3 134/4885KDM4E 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.