Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 5/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.53 |
| ▸ | WNT3A | P56704 | 9/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317600 | 0.90 | MAPK10 (0.62) | MAPK8MAPK10WNT3AHDAC1HDAC2 | |
| SCHEMBL2317072 | 0.86 | MAPK8 (0.52) | MAPK8MAPK10WNT3AHDAC1HDAC2 | |
| SCHEMBL12283692 | 0.86 | USP30 (0.55) | WNT3AHDAC1HDAC2USP30MEN1 | |
| SCHEMBL2318039 | 0.83 | MAPK8 (0.47) | MAPK8MAPK10HDAC1HDAC2MAPK14 | |
| SCHEMBL2317284 | 0.83 | FAAH (0.53) | WNT3AHDAC1HDAC2NPC1TSHR | |
| SCHEMBL2315666 | 0.77 | KMT2A (0.56) | WNT3AHDAC1HDAC2NPC1KMT2A | |
| SCHEMBL27859361 | 0.75 | HDAC1 (0.55) | MAPK8MAPK10HDAC1HDAC2USP30 | |
| SCHEMBL2320672 | 0.74 | WNT3A (0.53) | WNT3AHDAC1HDAC2USP30 | |
| SCHEMBL2317904 | 0.74 | DEGS1 (0.53) | WNT3AHDAC1HDAC2USP30 | |
| SCHEMBL2315755 | 0.74 | USP30 (0.52) | WNT3AHDAC1HDAC2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272120-B | Biologically active amides | LUNDBECK & CO AS H | 2013-12-25 | — | — | CN | disclosed |
| CN-102272120-A | Biologically active amides | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | NPY5R, NPY1R, NPY2R | MAPK8 3499/4885MAPK10 3482/4885WNT3A 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.