Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.78 |
| ▸ | MAOA | P21397 | 16/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175614 | 0.87 | DYRK1A (1.00) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL3848233 | 0.85 | MAOA (0.82) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL12071305 | 0.84 | MAOA (1.00) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL1180301 | 0.84 | MAOA (0.81) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL13874909 | 0.84 | MAOA (0.85) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL3847873 | 0.84 | MAOA (0.81) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL15227870 | 0.83 | MAOA (0.75) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL17520095 | 0.83 | MAOA (0.79) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL21393272 | 0.82 | MAOA (0.70) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL2566168 | 0.82 | MAOA (0.73) | DYRK1AMAOAKDM4EDYRK3CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094950-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094950-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | CSNK1A1, CSNK1E, CSNK1G3 | DYRK1A 7/4885MAOA 1312/4885KDM4E 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.