Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318338 | 0.94 | MAPK14 (0.61) | MAPK14METAP1 | |
| SCHEMBL2601324 | 0.86 | METAP1 (0.60) | MIFMETAP1CYP26A1CYP19A1 | |
| SCHEMBL7491470 | 0.81 | MAPK14 (0.56) | MIFMAPK14METAP1ALDH1A1MAPT | |
| SCHEMBL3759572 | 0.81 | MAPK14 (0.64) | MIFMAPK14ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6176649 | 0.81 | SLC6A15 (0.57) | MIFALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8166049 | 0.80 | MIF (0.77) | MIFALDH1A1MAPTSMN1; SMN2CYP26A1 | |
| SCHEMBL12204782 | 0.80 | CYP26A1 (0.63) | MIFALDH1A1MAPTSMN1; SMN2CYP26A1 | |
| SCHEMBL17108416 | 0.80 | MPO (0.59) | MIFMETAP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4148213 | 0.79 | METAP1 (0.50) | MIFMETAP1CYP19A1 | |
| SCHEMBL268592 | 0.79 | KDM4E (0.56) | MIFMETAP1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206534-A1 | Dibenzocycloheptanone derivatives und pharmaceutical agents containing these compounds | c-a-i-r biosciences GmbH (DE) | 2010-07-14 | — | — | EP | claimed |
| EP-2349964-B1 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C A I R BIOSCIENCES GMBH (DE) | 2015-09-09 | — | — | EP | disclosed |
| EP-2349964-B1 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C A I R BIOSCIENCES GMBH (DE) | 2015-09-09 | — | — | EP | disclosed |
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
| EP-2349964-A2 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | c-a-i-r biosciences GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| EP-2206534-A1 | Dibenzocycloheptanone derivatives und pharmaceutical agents containing these compounds | c-a-i-r biosciences GmbH (DE) | 2010-07-14 | — | — | EP | disclosed |
| EP-2206534-A1 | Dibenzocycloheptanone derivatives und pharmaceutical agents containing these compounds | c-a-i-r biosciences GmbH (DE) | 2010-07-14 | — | — | EP | disclosed |
| WO-2010040843-A2 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010040843-A2 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | IL1B, NFKBIA, IL1R1 | MIF 411/4885MAPK14 2812/4885METAP1 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.