Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 14/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317766 | 1.00 | TSPO (0.46) | TSPOELANECTRCPDE6DPLA2G7 | |
| SCHEMBL2321922 | 0.90 | TSPO (0.47) | TSPOELANECTRCPDE6D | |
| SCHEMBL2321927 | 0.90 | TSPO (0.47) | TSPOELANECTRCPDE6D | |
| SCHEMBL4774551 | 0.84 | TSPO (0.43) | TSPOPDE6DPLA2G7 | |
| SCHEMBL2358720 | 0.83 | ELANE (0.49) | ELANE | |
| SCHEMBL2358717 | 0.83 | ELANE (0.49) | ELANE | |
| SCHEMBL2319278 | 0.76 | XIAP (0.40) | ELANE | |
| SCHEMBL2319283 | 0.76 | XIAP (0.40) | ELANE | |
| SCHEMBL2319275 | 0.76 | XIAP (0.40) | ELANE | |
| SCHEMBL2316297 | 0.75 | ELANE (0.36) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989441-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-08-02 | — | — | US | claimed |
| US-20090069294-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-03-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069294-A1 | Organic Compounds | XIAP, BAX, MCL1 | TSPO 1398/4885ELANE 2303/4885CTRC 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.