Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FGB | P02675 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613253 | 0.82 | MAPT (0.39) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL23178258 | 0.82 | MAPT (0.39) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL29613360 | 0.80 | BCHE (0.36) | KDM4EHPGDSMN1; SMN2BCHEACHE | |
| SCHEMBL23178526 | 0.80 | BCHE (0.36) | KDM4EHPGDSMN1; SMN2BCHEACHE | |
| SCHEMBL29613266 | 0.73 | HSD11B1 (0.39) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23178256 | 0.73 | HSD11B1 (0.39) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29613254 | 0.71 | MAPT (0.36) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL23178295 | 0.71 | MAPT (0.36) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL23178525 | 0.70 | TRPV1 (0.33) | MAPTKDM4EHPGDBCHEACHE | |
| SCHEMBL23178114 | 0.66 | ACP1 (0.36) | HPGDOPRM1OPRL1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058114-A1 | DIHYDROQUINOLINE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, LTD. (IE) | 2021-04-01 | — | — | WO | disclosed |